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RivX sRNA
RivX sRNA is a non-coding RNA molecule involved in the interface between two key regulators of virulence in the human pathogen ''Streptococcus pyogenes'' (Group A ''Streptoccus'', also known as GAS): the CovR/S system and Mga regulator. This RNA, along with its downstream protein-coding gene ''RivR'', are the first discovered links between these two important regulation networks.〔 An extra protein linking the two pathways, TrxR, was described a year later. The adjoining of these two pathways could allow a consistently high virulence of ''S. pyogenes'' despite a variety of environmental conditions.〔 RivX is thought to be co-transcribed with RivR mRNA before post-transcriptional processing releases the sRNA. It was found to be a non-coding transcript through site-directed mutagenesis experimentation.〔 In total, the GAS genome is now predicted to encode 75 total sRNAs, a number approximately equal to the number of transcription factors encoded by the genome, which shows the importance of RNA regulation in GAS. ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「RivX sRNA」の詳細全文を読む
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